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ROSEANNE

What changed:A few weeks after the controversy — and after more questionable tweets from Barr —ABC announced it was moving forwardwith a spin-off calledThe Conners, bringing back theRoseannecast sans Barr, and a slightly new storyline, later in 2018.
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HOUSE OF CARDS
Netflix

What happened:In late 2017, Emmy nominee Kevin Spacey wasaccused of sexual assault and harassment. Netflix ultimately shut down production on the series, but later decided to revive the show without its star.
03of 10SUITSIan Watson/USA NetworkWhat happened:Longtime starPatrick J. Adams, a.k.a. Mike Ross, chose to leave on his own terms at the end of season 7 in 2018 (at the same time his costarMeghan Markleleft for …well, you know why).What changed:It remains to be seen, as the show isn’t back until 2019, but expect to see frequent guests Dulé Hill and Amanda Schull in expanded roles,plus new castmate Katherine Heigl.
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SUITS
Ian Watson/USA Network

What happened:Longtime starPatrick J. Adams, a.k.a. Mike Ross, chose to leave on his own terms at the end of season 7 in 2018 (at the same time his costarMeghan Markleleft for …well, you know why).
What changed:It remains to be seen, as the show isn’t back until 2019, but expect to see frequent guests Dulé Hill and Amanda Schull in expanded roles,plus new castmate Katherine Heigl.
04of 108 SIMPLE RULESWhat happened:Series patriarchJohn Ritter died suddenlyon Sept. 11, 2003, after experiencing some discomfort on set that morning. The cause of death was later determined to be an aortic dissection.What changed:The show went on. Ritter had filmed three episodes for the new season; after those aired, his character Paul Hennessydied suddenly of a heart attackwhile running errands. James Garner and Suzanne Pleshettejoined the castto play his in-laws, and the sitcom continued for two more years.
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8 SIMPLE RULES

What happened:Series patriarchJohn Ritter died suddenlyon Sept. 11, 2003, after experiencing some discomfort on set that morning. The cause of death was later determined to be an aortic dissection.
What changed:The show went on. Ritter had filmed three episodes for the new season; after those aired, his character Paul Hennessydied suddenly of a heart attackwhile running errands. James Garner and Suzanne Pleshettejoined the castto play his in-laws, and the sitcom continued for two more years.
05of 10LAVERNE & SHIRLEYSilver Screen Collection/GettyWhat happened:Though the ’70s series centered on the friendship of Laverne DeFazio (Penny Marshall) and Shirley Feeney (Cindy Williams), its last season was just Laverne, asa pregnant Williams departed the show.What changed:Not much; the show’s eighth and final season, which remained popular, just followed Laverne, then was quietly canceled.
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LAVERNE & SHIRLEY
Silver Screen Collection/Getty

What happened:Though the ’70s series centered on the friendship of Laverne DeFazio (Penny Marshall) and Shirley Feeney (Cindy Williams), its last season was just Laverne, asa pregnant Williams departed the show.
What changed:Not much; the show’s eighth and final season, which remained popular, just followed Laverne, then was quietly canceled.
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CHARLIE’S ANGELS
ABC via Getty

What changed:Cheryl Ladd succeeded Fawcett in a new role as her younger sister. The show continued on for four more seasons, though continued casting changes led to declining ratings.
07of 10SPIN CITYWhat happened:After four seasons on the ABC hit, star Michael J. Foxannounced his departurein 1998 to spend more time with family in the wake of his Parkinson’s diagnosis. The network took some time to decide if it wanted to continue without him, ultimately bringing in Charlie Sheen to play the new deputy mayor.What changed:Ratings actually went up for a while, as Sheen brought a new dynamic to the series (costarring Heather Locklear,who called the revamp “sexier”). It ended after six seasons, in 2002.
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SPIN CITY

What happened:After four seasons on the ABC hit, star Michael J. Foxannounced his departurein 1998 to spend more time with family in the wake of his Parkinson’s diagnosis. The network took some time to decide if it wanted to continue without him, ultimately bringing in Charlie Sheen to play the new deputy mayor.
What changed:Ratings actually went up for a while, as Sheen brought a new dynamic to the series (costarring Heather Locklear,who called the revamp “sexier”). It ended after six seasons, in 2002.
08of 10TWO AND A HALF MENCliff Lipson/CBS Photo Archive via GettyWhat happened:Charlie Sheen. The show’s star entered rehab in 2010 and announced he was leaving the popular CBS sitcom, though later signed a new contract. However, he returned to rehab in 2011, and at the same time disparaged the show’s creator Chuck Lorre in a series of interviews. CBS and Warner Bros. jointly dropped Sheen not long after.What changed:Sheen’s character Charlie Harper was dramatically killed off, and Ashton Kutcher came on for the final four seasons in a lead role alongside remaining star Jon Cryer.
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TWO AND A HALF MEN
Cliff Lipson/CBS Photo Archive via Getty

What happened:Charlie Sheen. The show’s star entered rehab in 2010 and announced he was leaving the popular CBS sitcom, though later signed a new contract. However, he returned to rehab in 2011, and at the same time disparaged the show’s creator Chuck Lorre in a series of interviews. CBS and Warner Bros. jointly dropped Sheen not long after.
What changed:Sheen’s character Charlie Harper was dramatically killed off, and Ashton Kutcher came on for the final four seasons in a lead role alongside remaining star Jon Cryer.
09of 10VALERIEWhat happened:Star Valerie Harper, who played family matriarch Valerie Hogan, asked for a raise and — execs said no, instead showing her the door.She eventually won a multi-million dollar settlementagainst the production company.What changed:After killing off Harper’s character, producers brought in Sandy Duncan to play her sister-in-law Sandy Hogan, renaming the showValerie’s Familyand later,The Hogan Family.
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VALERIE

What happened:Star Valerie Harper, who played family matriarch Valerie Hogan, asked for a raise and — execs said no, instead showing her the door.She eventually won a multi-million dollar settlementagainst the production company.
What changed:After killing off Harper’s character, producers brought in Sandy Duncan to play her sister-in-law Sandy Hogan, renaming the showValerie’s Familyand later,The Hogan Family.
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THREE’S COMPANY

What changed:Jenilee Harrison was brought in to play a cousin of Somers' former character. A second blonde, Priscilla Barnes, joined the next season, and the show continued until 1984.
source: people.com